SYN®-COLL DATA



What is
SYN®-COLL and How Does it Work?
SYN®-COLL is based on a small peptide developed to reduce any type of wrinkles. Clinical trials have shown that SYN®-COLL is capable of reducing and changing the type and aspect of wrinkles that add years to your appearance. Try it and you will see the difference within a short time.
The first signs of aging in the skin typically begin with superficial wrinkles. Therefore it is easily understandable that anti-wrinkle products play an important part as anti-aging products. Over the last few years peptides became an important part among the wrinkle reducing products. SYN®-COLL is an aqueous, unpreserved, glycerin based solution of a small peptide. It stimulates the collagen synthesis in human fibroblasts.

Syn Coll1 Syn Coll2
MACRO-PHOTOGRAPHS
Macro-photographs are done with a Nikon® D1 digital camera. The photographs are taken in standardized, indirect light.
Vol. 18 – day 0 Vol. 18 - day 84
After 84 days of twice-daily application of 2.5% SYN®-COLL parameters average relief (Rz) and maximum relief (Rt) significantly decreased by -12%: -22 μm and -36 μm respectively (p= 0.05) characterizing smoothing and anti-wrinkle effects.
COMPARISON OF PRODUCT EFFICACY
Both products have been used at the recommended use level. SYN®-COLL at 2.5% (25 ppm peptide) and the reference substance Palmitoyl Pentapeptide at 10 ppm (equivalent to a use level of 10% of the market available product calculated for the active peptide). SYN®-COLL clearly showed a higher efficacy for all tested parameters.
ADDITIONAL INFORMATION
Moreover, according to the answers of the objective evaluation questionnaire, the majority of the volunteers have appreciated the products for their organoleptics characteristics (aspect, texture, facility of spreading and penetration). A majority have noticed freshness and moisturizing sensation after application. More than 60% of all volunteers reported a general modification of the skin and an improvement of the crow’s feet at the same time. 93% of the volunteers will continue the use of a SYN®-COLL containing formula.
CONCLUSION
Clinical trials have shown that the active principle of SYN®-COLL is capable of reducing and changing the type and aspect of wrinkles that add years to your appearance.

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